Mesothelioma

MESOTHELIOMA

Mesothelioma is a rare form of cancer that is caused by exposure to asbestos. Mesothelioma cancer comes from inhaling or digesting asbestos dust particles. Mesothelioma cancer affects the abdominal cavity, chest cavity, and the region surrounding the heart.

Mesothelioma is a life-threatening disease and should not be left untreated. Most cases of mesothelioma begin in the pleura or peritoneum.

Mesothelioma cancer occurs in the mesothelium, a thin layer of tissue that covers your internal organs. The mesothelium is a membrane that covers and protects most of the internal organs of the body. There are two layers of cells in the mesothelium; one layer surrounds the organs; the other layer forms a sac around the organs.

Mesothelioma is most common in the pleura (the outer lining of the lungs and chest cavity), but it may also occur in the peritoneum (the lining of the abdominal cavity) or the pericardium (the sac that surrounds the heart).

NEW MESOTHELIOMA CASES

It has been well documented for many years that asbestos exposure can result in the development of deadly cancers, particularly Mesothelioma.

Mesothelioma has a latency period of 20 to 50 years after the first exposure to asbestos. It is estimated that there will be about 250,000 cases of Mesothelioma before 2020.

There are currently about 3000 new cases of Mesothelioma diagnosed per year, mostly in men over the age of 40.

About 4,000 People die each year from Mesothelioma. During the 20th century, some 30 million tons of asbestos were used in industrial sites, homes, schools, shipyards and commercial buildings in the U. S.

More than 700,000 people have filed claims against more than 6,000 Asbestos companies.

These same companies knew of the dangers for many years before ever warning the public of those risks. It is thought that around eight million people in the United States have been exposed to asbestos over the past half a century, and many more cases - are expected to be reported in the next 25 years.

MESOTHELIOMA EXPOSURE

The National Institute of Health in 1978 estimated that eight to eleven million U.S. workers had been exposed to asbestos by that date. In fact, by 1970, it is estimated that some 25 million tons of asbestos were used in the U.S.
People all over the world have been poisoned by toxic levels of asbestos, putting them at risk for mesothelioma, asbestosis, lung cancer, and other deadly diseases that are directly caused by the inhalation and digesting of asbestos fibers.
Asbestos was used in thousands of products that humans and animals encounter on a daily basis particularly in building components such as ceiling and floor tiles, walls, bricks and stucco, and in automotive parts such as brakes and clutches.
Workers who have mesothelioma have labored for years in jobs that required frequent contact with asbestos. When asbestos is mined, processed, woven, sprayed or otherwise manipulated, its microscopic fibers can be released into the air, where they may be inhaled, initiating the development of mesothelioma.

MESOTHELIOMA SYMPTOMS

mesothelioma symptoms include shortness of breath due to pleural effusion (fluid between the lung and the chest wall) or chest wall pain, and general symptoms such as weight loss

Mesothelioma signs and symptoms:

• abdominal pain
• bowel function problems
• chest wall pain
•  weight loss
• pleural effusion, or fluid surrounding the lung
• shortness of breath
• fatigue or anemia
• wheezing, hoarseness, or cough
• blood in the sputum (fluid) coughed up (hemoptysis)

Mesothelioma signs and symptoms in severe cases:

• blood clots in the veins, which may cause thrombophlebitis
• disseminated intravascular coagulation, a disorder causing severe bleeding in many body organs
• jaundice, or yellowing of the eyes and skin
• low blood sugar level
• pleural effusion
• pulmonary emboli, or blood clots in the arteries of the lungs
• severe ascites

MESOTHELIOMA TYPES

Mesothelioma can attack the pleural lining around the lungs. It can also attack the peritoneum, a tissue that surrounds the GI tract. Mesothelioma can attack the stomach lining, other internal organs, or even the pericardium (the tissue sac covering the heart). Thus, mesothelioma can be generally classified into the following types:

• Pleural — 75% of all mesothelioma cases
• Peritoneal — 10%–20%
• Pericardial — 5%

Mesothelioma Types

• Epithelioid — most common, best survival rate
• Sarcomatoid — most severe, but more rare
• Mixed/biphasic — a mixture of epithelioid and sarcomatoid cancer

MESOTHELIOMA DIAGNOSIS

If you think that you may have been exposed to asbestos at any time, it is important to share your concern with a physician.
Mesothelioma is a very aggressive form of cancer, and one of the reasons that it has such a low survival rate is because it is not typically diagnosed until the disease is fairly advanced.

Diagnosis of Mesothelioma is based on a pathological exam, more commonly referred to as a biopsy. This exam will test a tissue sample for the presence of malignant and/or pleural mesothelioma.

Mesothelioma diagnosis begins with a review of the patient's medical history. A history of exposure to asbestos is a common theme in diagnosing mesothelioma.
Mesothelioma diagnosis is often difficult, because the symptoms are similar to those of a number of other conditions.
Mesothelioma diagnosis includes a physical examination followed by chest X-rays and a CT scan, and confirmed with a biopsy (tissue sample) and microscopic examination.

To diagnose mesothelioma a thoracoscopy (inserting a tube with a camera into the chest) is used to do a biopsy.
Individuals with pleural mesothelioma may accumulate some fluid between the lung lining and chest cavity. This can be detected through a chest x-ray, as well as CT scans.

MESOTHELIOMA TREATMENT  

Treatment for mesothelioma using conventional therapies has not proved successful and patients have a median survival time of 6 - 18 months depending on which stage (1-4) the mesothelioma cancer has progressed.

Treatments for Mesothelioma

Research into new and more effective treatments for mesothelioma is ongoing. There is no cure as yet for mesothelioma. The standard treatments that attempt to hold back the progression of this cancer are:

• Surgery — to remove part of all of the affected body tissues
• Radiation therapy — to target and kill the mesothelioma cells
• Chemotherapy — the use of drugs, injected or taken orally, to kill or stop the growth of the cancer cells

Mesothelioma treatment depends on the location of the cancer, the stage of the disease, and the patient’s age and general health. Standard treatment options include surgery, radiation therapy, and chemotherapy. Sometimes, these treatments are combined.

MESOTHELIOMA DRUGS

In February 2004, the U. S. Food and Drug Administration (FDA) approved pemetrexed (brand name Alimta) for treatment of mesothelioma. Pemetrexed is given in combination with cisplatin. Folic acid is also used to reduce the side-effects of pemetrexed.

MESOTHELIOMA AND SMOKING

Unlike lung cancer, there is no association between mesothelioma and smoking.
Smoking does not appear to increase the risk of mesothelioma. However, the combination of smoking and asbestos exposure significantly increases a person’s risk of developing cancer of the lungs.

The Kent brand of cigarettes used asbestos in its filters for the first few years of production in the 1950s and some cases of mesothelioma have resulted. Smoking modern cigarettes does not appear to increase the risk of mesothelioma.
The combination of smoking and asbestos exposure significantly increases a person's risk of developing cancer of the airways (lung cancer, bronchial carcinoma).
If you do smoke, stop. In addition to mesothelioma and asbestosis, there is research that indicates that those who suffer from asbestos exposure and smoke are at a greatly increased risk of developing mesothelioma lung cancer.

Mesothelioma symptoms may not appear until 20 to 50 years after exposure to asbestos.
Mesothelioma occurs more often in men than in women and risk increases with age, but this disease can appear in either men or women at any age.
Working with asbestos is the major risk factor for mesothelioma. A history of asbestos exposure in the workplace is reported in about 70 percent to 80 percent of all cases.

Mesothelioma will cause shortness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space.
Mesothelioma does not usually spread to the bone, brain, or adrenal glands. Pleural mesothelioma tumors are usually found only on one side of the lungs.
Family members and others living with asbestos workers have an increased risk of developing mesothelioma, and possibly other asbestos related diseases.
Early Mesothelioma screening tests can diagnose mesothelioma earlier than conventional methods thus improving the survival prospects for patients.

Mesothelioma is described as localized if the cancer is found only on the membrane surface where it originated.

Mesothelioma is classified as advanced if it has spread beyond the original membrane surface to other parts of the body, such as the lymph nodes, lungs, chest wall, or abdominal organs.

The first lawsuits against asbestos manufacturers were in 1929. Since then, many lawsuits have been filed against asbestos manufacturers and employers, for neglecting to implement safety measures after the links between asbestos, asbestosis, and mesothelioma became known (some reports seem to place this as early as 1898).
A good Mesothelioma attorney understands the unique complexities involved in this kind of litigation lawsuit, including asbestos product identification, specific asbestos-related medical issues, and specific time constraints that narrow the window of opportunity to file a claim.
It is important to find the right Mesothelioma lawyer before your state’s statutes of limitations expires, leaving you and your family grieving and empty-handed. There's no time to wait - contact our mesothelioma lawyers today for a free case review.
We have helped many people get experienced legal and medical help for their mesothelioma cancer and asbestos cancer cases. We will actually walk you the process of contacting an experienced mesothelioma lawyer that we have worked with to get you the best possible settlement for your mesothelioma case.

It is not uncommon for there to be 10-20 parties that are named in a mesothelioma lawsuit that are located across the United States. For example, a worker in California may have been exposed to asbestos from asbestos products shipped from Libby, Montana or from an iron ore plant in St. Paul Minnesota. This is why it is very important to obtain an experienced mesothelioma lawyer knows all of the companies in each state who have responsibility for your asbestos exposure.

We have helped people with mesothelioma cancer for more than five years on the Internet. The Mesothelioma Help Center is designed to give you quick & simple answers about mesothelioma treatments, asbestos exposure, mesothelioma diagnosis, mesothelioma symptoms, mesothelioma doctors, and we can refer you to an experienced mesothelioma lawyer in who has successfully settled mesothelioma cases.